Iodine Brachytherapy for Large Uveal Melanomas

نویسندگان

  • Ilkka Puusaari
  • Patrick De Potter
  • Winfried Alberti
  • Benjamin Franklin
چکیده

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Uveal Melanoma Research and Treatment at Mayo Clinic

Mayo Clinic in Rochester, Minnesota, has a long history in the treatment of uveal melanomas. In the early 1980s, Dennis Robertson, MD, was one of the first to use iodine-125 plaques, the form of brachytherapy most commonly used for treatment of uveal melanomas in the United States today. The plaques used in the Collaborative Ocular Melanoma Study (COMS), a multicenter study initiated in 1985 to...

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103Pd versus 125I ophthalmic plaque brachytherapy: preoperative comparative radiation dosimetry for 319 uveal melanomas

OBJECTIVE This study was conducted to compare the relative, clinical intraocular dose distribution for palladium-103 (103Pd) versus iodine-125 (125I) ophthalmic plaque radiation therapy. METHODS Preoperative comparative radiation dosimetry was performed to evaluate 319 consecutive uveal melanomas treated between 2006 and 2012. RESULTS There were 68 (21.3 %) anterior (iris and/or ciliary bod...

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Ruthenium-106 Brachytherapy for Uveal Melanomas – Preliminary Results: a Single Institutional Experience*

OBJECTIVE: To analyze the early response of uveal melanomas in patients treated with ruthenium-106 brachytherapy. MATERIALS AND METHODS: In the period between April 2002 and July 2003, 20 patients diagnosed with uveal melanoma were submitted to ruthenium-106 brachytherapy. The calculated dose delivered at the apex of the tumor ranged between 55 Gy and 100 Gy. Patients with lesions greater than ...

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The investigators' perspective on the collaborative ocular melanoma study.

bling times in metastatic malignant melanoma of the uvea: tumor progression before and after treatment. Ophthalmology. 2000;107(8):1443-1449. 8. Clarke M, Collins R, Darby S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;366(9503):2087-2106. 9. Presch...

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Proton beam therapy for the treatment of uveal melanoma in Scotland.

BACKGROUND AND AIMS In Scotland, uveal melanomas are primarily treated with eye-preserving modalities with a low primary enucleation rate. Proton beam therapy (PBT) is reserved for those not suitable for brachytherapy. The authors' aim was to review the outcome of Scottish patients undergoing treatment for uveal melanoma with PBT. METHOD All ciliary body or choroidal melanomas treated initial...

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تاریخ انتشار 2006